Released on: October 14, 2008, 1:14 am

Press Release Author: The Scott Partnership

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Press Release Summary: SAN JOSE, Calif. (October 13, 2008) - Thermo Fisher
Scientific Inc., the world leader in serving science, today announced the launch of
MetWorks 1.2, an updated version of its successful metabolite identification
software.
Thermo Scientific MetWorks is a powerful data-mining tool for small molecules that
can be used to search for and identify a variety of metabolites with a high degree
of accuracy and confidence. Thermo Fisher will showcase the newest capabilities of
MetWorks at the 15th North American Regional ISSX Meeting in San Diego, California
on October 12-16, 2008.

Press Release Body: FOR IMMEDIATE RELEASE
Mass Spectrometry
Media Contact Information:
Name: Laura Browne/Charlotte Culley
Phone: +44 1477 539539
Email: thermo@scottpr.com
Website: www.scottpr.com

Secondary Contact Information:
Stephanie Kubina
+1 (408) 965-6022
stephanie.kubina@thermofisher.com

Thermo Fisher Scientific Launches MetWorks 1.2 for Accurate Metabolite Identification

SAN JOSE, Calif. (October 13, 2008) - Thermo Fisher Scientific Inc., the world
leader in serving science, today announced the launch of MetWorks 1.2, an updated
version of its successful metabolite identification software.
Thermo Scientific MetWorks is a powerful data-mining tool for small molecules that
can be used to search for and identify a variety of metabolites with a high degree
of accuracy and confidence. Thermo Fisher will showcase the newest capabilities of
MetWorks at the 15th North American Regional ISSX Meeting in San Diego, California
on October 12-16, 2008.

MetWorks facilitates the acquisition, processing and reporting of liquid
chromatography/mass spectrometry data. Dr. Yingying Huang, strategic marketing
specialist for the metabolism and metabolomics group at Thermo Fisher Scientific,
explains: "Thanks to a range of new features, the latest version of the software
will dramatically simplify and speed up the search for expected and unexpected
biotransformations."

MetWorks 1.2 boasts a new graphical user interface (GUI) that exploits the power of
multiple mass defect filters (MMDF). Mass defect filtering is one of the most
powerful and sophisticated ways of using high-resolution mass data to obtain a
smaller, more refined data set for review. The interactive MMDF GUI displays the
distribution of parent and potential metabolites and allows both novice and expert
users to mine the data in a quick and easy manner. Combined with high-resolution
data from a Thermo Scientific LTQ Orbitrap mass spectrometer, MetWorks facilitates
extraction of low levels of metabolite ions, even when they are three to four orders
of magnitude less abundant than the background matrix ions, thus providing a
significantly enhanced signal-to-noise ratio.

This latest version of the software also features a new concise summary report that
conforms to industry standards, as well as provides accurate mass analysis data
(with ppm values). Additionally, there are new Analyte and Modification Managers
which automatically calculate accurate masses for parent compounds and potential
biotransformations using standard molecular formulae.

MetWorks software is compatible with all Thermo Scientific mass spectrometers
capable of performing MS/MS and MSn fragmentation. It takes advantage of
reproducible MSn fragmentation data and enables analysis of high-resolution accurate
mass data, available from the Thermo Scientific LTQ Orbitrap hybrid mass
spectrometer and LTQ FTTM Fourier transform instruments, to be fully exploited.

As Dr. Huang explains, "MetWorks 1.2 is powerful, easy to use and provides confident
and accurate results in less time. This enables researchers and developers working
in the pharmaceutical industry to streamline the drug discovery and development
processes. They will find this tool invaluable."

For more information on Thermo Scientific MetWorks software, as well as other Thermo
Scientific products, please visit Thermo Scientific booth 1 at the 15th North
American Regional ISSX Meeting in San Diego on October 12-16.
Alternatively, please call +1 800-532-4752, e-mail analyze@thermofisher.com or visit
www.thermo.com/metabolism.

Thermo Scientific is part of Thermo Fisher Scientific, the world leader in serving
science.

About Thermo Fisher Scientific
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science,
enabling our customers to make the world healthier, cleaner and safer. With annual
revenues of $10 billion, we have more than 30,000 employees and serve over 350,000
customers within pharmaceutical and biotech companies, hospitals and clinical
diagnostic labs, universities, research institutions and government agencies, as
well as environmental and industrial process control settings. Serving customers
through two premier brands, Thermo Scientific and Fisher Scientific, we help solve
analytical challenges from routine testing to complex research and discovery. Thermo
Scientific offers customers a complete range of high-end analytical instruments as
well as laboratory equipment, software, services, consumables and reagents to enable
integrated laboratory workflow solutions. Fisher Scientific provides a complete
portfolio of laboratory equipment, chemicals, supplies and services used in
healthcare, scientific research, safety and education. Together, we offer the most
convenient purchasing options to customers and continuously advance our technologies
to accelerate the pace of scientific discovery, enhance value for customers and fuel
growth for shareholders and employees alike. Visit www.thermofisher.com.

For further press information please contact: Laura Browne, The Scott Partnership, 1
Whiteside, Station Road, Holmes Chapel, Cheshire. CW4 8AA United Kingdom Tel: + 44
1477 539539 Fax: +44 1606 1477 539540 E-mail:
thermo@scottpr.com.

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Contact Details: Mass Spectrometry
Media Contact Information:
Name: Laura Browne/Charlotte Culley
Phone: +44 1477 539539
Email: thermo@scottpr.com
Website: www.scottpr.com

Secondary Contact Information:
Stephanie Kubina
+1 (408) 965-6022
stephanie.kubina@thermofisher.com